The present investigation has analyzed blood of mice infected with European genospecies, Borreliella afzelii or Borreliella garinii, or B. The obtained results were encouraging and prompted us to further investigate the RS diagnostic capacity for LD in this study. The selected strains represented two out of the three major clades of B. The previous investigation analyzed the blood from mice that were infected with 297 and B31 strains of Borreliella burgdorferi sensu stricto ( s.s.). Recently, Raman spectroscopy (RS) was examined for its LD diagnostic utility by our earlier proof-of-concept study. The main drawbacks of the two-tiered serology, the only approved diagnostic test in the United States, include poor sensitivity, background seropositivity, and cross-reactivity. LD is a multi-systemic and highly debilitating illness that is notoriously challenging to diagnose. Lyme disease (LD), the leading tick-borne disease in the Northern hemisphere, is caused by spirochetes of several genospecies of the Borreliella burgdorferi sensu lato complex. 3Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States.

2Lyme Disease Biobank, Portland, OR, United States.1Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, United States.Horn 2, Rohini Morey 1, Kyle McClellan 1, Dmitry Kurouski 1* and Artem S. Goff 1, Tianyi Dou 1, Samantha Higgins 1, Elizabeth J.

Spectra 10 with lyme